In a meta-analysis from the Journal of Arthritis Research and Therapy, diclofenac was found to be more effective than ibuprofen for arthritic pain relief. The study reviewed data from 176 studies with over 146,524 patients. The risk of stomach-related effects were also found to be lower with diclofenac compared to ibuprofen.
Diclofenac solution (Cambia) is used to treat migraine headaches in adults, but cannot be used to prevent migraines or to treat other types of headaches. Diclofenac is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.
Among the many NSAIDs available, ibuprofen, diclofenac, and ketoprofen remain the most frequently used . The principal guidelines for the long-term management of RA state that symptomatic RA patients should be treated with NSAIDs (together with a proton pump inhibitor if necessary) because they have an immediate effect on pain and stiffness
The active ingredient in Voltaren Arthritis Pain, diclofenac, may cause a severe allergic reaction, especially in people allergic to aspirin. If an allergic reaction occurs, consumers are advised
Scherger reports no financial relationship to this field of study. Synopsis: A systematic review of 9 studies showed that the COX-2 inhibitor celecoxib and ibuprofen cause less upper GI bleeding than other NSAIDs. Diclofenac, meloxicam, ketoprofen, indomethacin, and naproxen have intermediate risk. Piroxicam and ketorolac have the highest risk.
"The Agency does not have a position on the concept you have proposed," an official wrote back in an email. Whatever the solution, the drug industry will need to be spurred to change, says HussainX6HIU.